Rheumatoid Arthritis Pathophysiology

Gout: causal factors and symptoms Transformation of gout from the disease of kings to a common 21st century disease Genetic links to gout Treatment and prevention of gout References Further reading Around 3 million Americans have gout, an extremely painful arthritic condition. Historically, gout was called the "disease of kings" because it was thought to manifest due to overindulgence in food and alcohol. Scientists discovered that although some food products can exacerbate the condition, it occurs due to a higher concentration of uric acid (urate) in the blood, i.e., hyperuricemia. The uric acid crystals accumulate in the joints, which induces inflammation and triggers acute pain. Image Credit: sumroeng chinnapan/Shutterstock.com Gout: causal factors and symptoms Gout is a type of inflammatory arthritis which causes swelling, redness of the skin, and extreme pain in the joints of the knees, ankle, and big toes. It can also occur in the wris...

Treatments for psoriasis fall into four categories: topicals, phototherapy, systemics and complementary or integrative medicine, according to the NPF. The choice of therapy depends on the severity of the disease, says Dr. Green. Topical treatments are creams applied directly to the affected area, slowing the rapid production of skin cells and reducing inflammation. The most common topical medications are topical steroids, which contain an anti-inflammatory ingredient to heal swelling and redness and usually require a prescription from your doctor. However, topical steroids can't be used in some areas because they may cause side effects like bruising, pigmentation and redness. In 2022, the U.S. Food and Drug Administration (FDA) approved a new, nonsteroidal topical cream for adults for the first time in 25 years called tapinarof. "Patients can use this treatment from head to toe without any limitations, which is great for those who have mild to moderate psoriasis," sa...

[unable to retrieve full-text content] Best Diet for Gout: Dos and Don'ts    U.S. News & World Report

Human metapneumovirus (hMPV) is a viral illness that affects the upper respiratory tract. Several viruses can cause common cold symptoms, including hMPV.  With hMPV, symptoms such as runny and stuffy nose are common. People may experience more serious effects in some cases, but most don't develop serious symptoms. This article will take a closer look at the symptoms of human metapneumovirus, including frequent and rare symptoms and potential complications. It will also discuss when it might be time to seek medical help.  Geber86 / Getty Images Frequent Symptoms  Most people who contract human metapneumovirus experience mild cold symptoms such as: Runny nose Congestion Sore throat Cough Headache Fever Infants with human metapneumovirus may also experience weight loss. Most people with mild symptoms will feel better within a few days and won't require medical treatment. This virus most often c...

Bronchitis cough can be persistent and painful for the chest. In addition to taking medicine, you can try certain tips and remedies to ease the symptoms at home. According to Healthline, the anti-inflammatory properties of ginger can help with bronchitis symptoms. You can either chew it raw, add it to your salads and cooked dishes, or drink ginger tea. Similarly, Healthline recommends adding turmeric spice to your diet to alleviate symptoms of bronchitis. It is thought to have anti-viral and anti-bacterial properties. Plus, it promotes better immunity, decreasing your risk of future respiratory infections. Per WebMD, if the cough is persistent and interferes with your routine, you can try gargling a mix of salt and lukewarm water. It may help rid the mucus in the respiratory lining and has a soothing effect against throat irritation. Additionally, WebMD suggests mixing honey in tea for additional relief.  MedicalNewsToday recommends using a humidifier if bronchitis sympt...

Introduction The civilian use of firearms is a common cause of traumatic injury in the United States. It is estimated that an average of 120,232 firearm injuries occurred yearly from 2009 to 2017. 1 Knowledge regarding gunshot wound (GSW) injury and management was chiefly derived from experience garnered during the major wars of the 20th century. Existing guidelines were written when high velocity firearms and deforming rounds, which create more extensive tissue damage, were predominantly restricted to the military. However, advances in weapons technology and the increased accessibility of military grade firearms to civilians has changed the nature of domestic GSW injury, thereby complicating clinical decision-making. 2,3 Despite the prevalence of GSWs, especially in high volume trauma centers, treatment decisions are still largely driven by anecdotal beliefs. A common myth is that the heat produced by gun powder ignition during firearm discharge is sufficient to sterilize the b...

pet Published on Sep 08, 2022 08:31 PM IST Fever, runny nose, coughing, wheezing, difficult breathing, a decreased appetite, fatigue, and weight loss are some of the typical symptoms of pneumonia in dogs. Aspiration pneumonia, bacterial or viral infections in the respiratory system, breathing in foreign objects, inhaling fungus spores, and other conditions are a few of the causes of pneumonia in dogs(Unsplash) By Parmita Uniyal , Delhi Pneumonia is an inflammation of the air sacs of the lungs and can cause difficulty in breathing and coughing. The pulmonary condition can also affect dogs, cats and other animals apart from humans. Pneumonia in dogs can be easily treated if detected early and with proper treatment. There are different types of pneumonia that can affect your canine companion. Viral or bacterial pneumonia is most common while breathing in foreign material can cause aspiration pneumonia. It can also be contrac...

As fall arrives, cooler temperatures encourage people to spend more time outdoors. An expert at Baylor College of Medicine reminds allergy sufferers to be conscious of what is in the air and offers tips on how to protect yourself to enjoy the new season. "People frequently experience allergy symptoms in the fall even if they are mainly allergic to pollens in the spring and summer," said Dr. David Corry, professor of medicine in the section of immunology, allergy and rheumatology at Baylor. What to expect this season This year, the world saw several natural events that could impact the severity of the upcoming allergy seasons. The eruption of the Tonga Volcano in January launched a large number of particulates and aerosols into the air, Corry said, which may translate into a global weather event that could lengthen or shorten the pollen seasons in fall, winter or spring. He also said that due to the northern hemisphere experiencing hotter and drier weather this year, some regi...

Epidemiology A total amount of 8970 patients were admitted for AP during the study period, and 8637 AP patients were enrolled in the study. The incidence of tumor-induced AP was 1.16% (100/8637), and the incidence was increasing year by year. Up to now, the annual incidence rates of tumor-induced AP from 2013 to 2021 were 0.29% (2/680), 0.14% (1/713), 0.25% (2/805), 0.23% (2/852), 0.46% (5/1090), 0.34% (4/1187), 0.81% (8/983), 3.82% (40/1046) and 2.81% (36/1281). Among 3310 patients with AP from 2019 to 2021, miscellaneous causes included cholelithiasis (52.5%), hypertriglyceridemia (16.7%), idiopathic (12.7%), diet-related (9.5%), and infection (0.8%), alcohol (1.4%), autoimmune (0.4%), operation (1.5%), dialysis (0.1%), trauma (0.5%), congenital (0.1%), thrombosis (0.0%; 2 cases), pancreatolithiasis (0.5%), poisoning (0.2%), drugs (0.1%), tumor (2.4%), metastasis (0.2%), type 1 diabetes (0.0%; 2 cases), friction of drainage tube (0.0%; 2 cases), ileus (0.0%; 1 case), biliary hemorrha...